The trailer for Frank Zappa's 200 Motels:
The complete film is on Netflix.
I watched it the other day. It most closely resembles one of the weirder Python sketches -- like if you took, say, "Where Have All the Fishes Gone?" and stretched it to 100 minutes.
I found that, after two beers, it couldn't quite hold my full attention -- I imagine it would be more fun to watch with friends who are equally as interested in Weird Shit, and/or on stronger drugs, or possibly as background noise at a party, especially if it's late and most of the guests have gone home.